Flowers attract hummingbirds, butterflies, and many other nectar-seeking insects. Moth larval food plant for the Alfalfa Looper Moth (Autographa californica), Bilobed Looper Moth (Megalographa biloba), Virginian Tiger Moth (Spilosoma virginica), Wavy-Lined Emerald (Synchlora aerata), the geometrid Pherne subpunctata, and the plume moth (Anstenoptilia marmarodactyla).

There are 1045 species of Salvia all over the world. The genus name, salvia, comes from the Latin word salvia, which is related to the Latin words salvus (safe, healthy, secure) and salvēre (to heal, to feel healthy). The name refers to the medicinal properties of some plants in the genus. The species, mohavensis, refers to the Mojave Desert where it is found.

This species has many medicinal uses.

Desert dweller on well-drained sandy, gravelly, and rocky soils in washes and on upper bajadas and moderate slopes into the lower mountains of California, Nevada, Arizona, and Sonora. Mostly a Mojave Desert plant.